Saturday, January 24
|
| KEYNOTE LECTURE AND WELCOME RECEPTION |
| 18:00 |
Klaus Rajewsky |
Growing up as an immunologist among molecular geneticists |
| 19:00 |
Mix and Meet |
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Sunday, January 25
|
| MAKING AND SHAPING LYMPHOCYTES (1) |
| 09:00 |
Thomas Boehm |
Evolution of adaptive immunity |
| 09:30 |
Wan-Lin Lo |
Positive, negative, and everything in between |
| 10:00 |
Andreas Krüger |
Multi-step control of thymic selection by microRNA miR-181 |
| 10:15 |
Vera Martins |
Limiting bone marrow chimerism impairs thymic cell competition and causes leukemia |
| 10:30 |
Coffee Break |
|
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MAKING AND SHAPING LYMPHOCYTES (2)
|
| 11:00 |
Ludger Klein |
Determinants of central T cell tolerance |
| 11:30 |
Andrew Koh |
Vitamin D receptor modulates NF-κB bandwidth to promote thymic epithelial diversity for immunological tolerance |
| 11:45 |
Gleb Turchinovic |
Reconstruction of Innate Lymphoid Cell development in vitro |
| 12:00 |
Lunch Break |
|
|
AT THE CROSSROADS OF INNATE AND ADAPTIVE IMMUNITY (1)
|
| 14:00 |
Ranit Kedmi |
Immune tolerance to food and commensals: from induction to inflammation control |
| 14:30 |
Osamu Takeuchi |
RNA regulation in the innate immune system |
| 15:00 |
Chiara Romagnani |
Mechanisms of NK cell clonality |
| 15:30 |
Coffee Break |
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AT THE CROSSROADS OF INNATE AND ADAPTIVE IMMUNITY (2)
|
| 16:00 |
Adrian Hayday |
Regulation of innate immunity by a prototypic adaptive immune receptor |
| 16:30 |
Thomas Herrmann |
Cell type specific differences of immunmodulation and human γδTCR receptor binding by Butyrophin A1 |
| 16:45 |
Immo Prinz |
A stem-like Vδ1+ γδ T cell subset sustains effector responses to recurrent malaria infections |
| 17:00 |
Thomas Winkler |
A T cell receptor VDJδ knockin mouse reveals new NKT and IEL subpopulations of γδ T cells |
Monday, January 26
|
| SHAPING AND DIVERSIFYING T CELL FUNCTION |
| 09:00 |
Thomas Brocker |
Extracellular vesicles |
| 09:30 |
Wilfried Ellmeier |
Histone deacetylases and the regulation of T cell-mediated immunity |
| 10:00 |
Julia Polansky |
Proliferation-driven epigenetic plasticity promotes memory differentiation in human T lymphocytes |
| 10:15 |
Carmen Gerlach |
From T cell subsets to axes of diversification – a novel conceptual framework for understanding and measuring T cell diversification |
| 10:30 |
Coffee Break |
|
|
REGULATORY T CELLS (1)
|
|
| 11:00 |
Adrian Liston |
Molecular and cellular control of regulatory T cell tissue-residency |
| 11:30 |
Thomas Korn |
CD38 endows local antigen-specific Foxp3+ Treg cells with stress resilience for control of compartmentalized CNS inflammation |
| 11:45 |
Christina Jäger |
Inducible protein degradation reveals inflammation-dependent function of the Treg cell lineage-defining transcription factor Foxp3 |
| 12:00 |
Lunch Break |
|
|
REGULATORY T CELLS (2)
|
| 17:00 |
Nicole Joller |
Regulatory T cell specialization in Th1 responses |
| 17:30 |
Ari Glasner |
Orthogonal targeting of CCR8+ T regulatory cells (Tregs) and the TIGIT–PVR pathway enhances anti-tumor immunity |
| 17:45 |
Dominik Filipp |
Safeguarding early microbiota: the emerging role of Sca-1⁺ RORγt⁺ regulatory T cells |
| 18:00 |
Ari Waisman |
Aging-associated microbiota drives Treg cell dysfunction via TNF signaling |
| 18:15 |
Poster Session (1) |
Enjoy fingerfood and drinks |
Tuesday, January 27
|
| MYELOID CELL BIOLOGY |
| 09:00 |
Michael Sixt |
Energetics of leukocyte locomotion |
| 09:30 |
Caetano Reis e Sousa |
Dead cell recognition by dendritic cells and anti-cancer immunity |
| 10:00 |
Mirela Kuka |
Viral context dictates a cytotoxic monocyte program that may restrain B cell responses |
| 10:15 |
Marc Schmidt-Supprian |
Proteogenomic analyses of allergic mast cell activation |
| 10:30 |
Coffee Break |
|
|
IMMUNE CELLS IN SPACE AND TIME (1)
|
| 11:00 |
Donna Farber |
Establishment and maintenance of tissue resident immunity across the lifespan |
| 11:30 |
David Masopust |
Memory CD8 T cells: quantity, quality & location |
| 12:00 |
Lunch Break |
|
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IMMUNE CELLS IN SPACE AND TIME (2)
|
| 17:00 |
Matteo Iannacone |
Immune surveillance of the liver |
| 17:30 |
Georg Gasteiger |
Strategic positioning of Tcf7hi CD8+ memory T cells in the liver enables rapid detection of systemic infection |
| 17:45 |
Jan Dobes |
SFB-induced intraepithelial lymhocyte differentiation: the critical molecular and cellular players |
| 18.00 |
Poster Session (2) |
Enjoy fingerfood and drinks |
Wednesday, January 28
|
| AUTOIMMUNITY |
| 09:00 |
Daniela Latorre |
Autoreactive T cells in inflammatory peripheral neuropathies |
| 09:30 |
Georg Schett |
CAR T cell therapy in autoimmune diseases |
| 10:00 |
Günter Steiner |
Identification of novel autoantibodies for diagnosing seronegative rheumatoid arthitis |
| 10:15 |
Isabell Serr |
Antigen-specific immune modulation with liver-targeting nanoparticles fosters immune protective regulatory T cells to delay Type 1 Diabetes |
| 10:30 |
Coffee Break |
|
|
LYMPHOCYTE ACTIVATION AND HOMEOSTASIS
|
| 11:00 |
Wolfgang Kastenmüller |
Dendritic cells initiate T cell exhaustion through a systemic feedback mechanism |
| 11:30 |
Jörg Kirberg |
Lymph node heterogeneity offsets competitive homeostatic exclusion among peripheral T cells |
| 11:45 |
Daniel Krappmann |
MALT1 alternative splicing – a molecular rheostat for tuning immune activation and homeostasis |
| 12:00 |
Lunch Break |
|
|
CANCER IMMUNOLOGY
|
| 14:00 |
Naomi Taylor |
Harnessing CAR precision: metabolic constraints, hinges, and fuzzy logic |
| 14:30 |
Michel Sadelain |
Evolution of natural and synthetic receptors for antigen |
| 15:00 |
Alina Shomuradova |
From TCR–CD3 architecture to synthetic receptors with tunable antigen discrimination |
| 15:15 |
Shi Yong Neo |
Nur77 agonism invigorates Natural Killer cell immunity against hepatocellular carcinoma |
| 15:30 |
Coffee Break |
|
|
HUMORAL IMMUNITY AND VACCINATION
|
| 16:00 |
Hedda Wardemann |
Malaria vaccine development |
| 16:30 |
Annagiulia Scognamiglio |
Novel encoded adjuvants for genetic vaccines |
| 16:45 |
Taras Kreslavsky |
Determinants of longevity,diversity and rapid responsiveness of B cell memory |
|
FAREWELL LECTURE
|
| 17:00 |
Meinrad Busslinger |
Farewell Lecture: Transcriptional Control of humoral immunity |
| 19:00 |
Tyrolean Evening |
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